Madras Agricultural Journal
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Research Article | Open Access | Peer Review

Antifungal Bioactive Compounds from Chinese Caterpillar Fungus (Ophiocordyceps sinensis (Berk.) G. H. Sung et al.) against Plant Pathogens

Volume : 102
Issue: Oct-dec
Pages: 353 - 357
Published: April 30, 2023
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Abstract


Studies were conducted to extract and evaluate the intracellular bioactive molecules of Ophiocordyceps sinensis against plant pathogens. Methanolic fraction of mycelium borne bioactive molecules at 200 μL concentration showed the maximum mycelial inhibition of Fusarium oxysporum f. sp. cubense (48.67 per cent) and F. o. f. sp. lycopersici (46.47 per cent), which cause wilt disease in banana and tomato, respectively. GC-MS analysis of methanolic fraction of mycelial mat extract indicated the presence of 14 different compounds hydroxylamine; glycerin; oxime-,methoxy-phenyl; adipamide; 1,2,3-Benzenetriol; cyclododecane; imidazole-5-carboxylic acid; 1,3,5-Benzenetriol; 1,3-Cyclohexanedione, 2-propyl; 2-Propenoic acid, tridecyl ester; n-Decanoic acid; 5-Undecene, 9-methyl; L-Ornithine, N5-(aminocarbonyl) and pyrrolo [1,2-a]pyrazine-1,4-dione, hexahydro. Among these, the compound hydroxylamine identified at 1.817 RT exhibited the maximum peak area of 35.00 per cent. This compound is also known to possess important pharmacological and antimicrobial properties.

DOI
Pages
353 - 357
Creative Commons
Copyright
© The Author(s), 2025. Published by Madras Agricultural Students' Union in Madras Agricultural Journal (MAJ). This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited by the user.

Keywords


O. sinensis Antifungal bio-molecules TLC and GC-MS
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