Field experiment was conducted in Bidhan Chandra Krishi Viswavidyalaya, Kalyani, West Bengal during the Kharif seasons of 2009 and 2010 with an objective of location specific eco-safe herbicide management of Parthenium and microbial activity in soil. The experiment was laid out in randomized block design where each treatment was replicated seven times. The Chemical management was done by using Glyphosate 71 SG + 2, 4- D ammonium salt ready mixture @ 3 kg ha-1; Glyphosate 71 SG @ 3 kg ha-1 and control. The highest Parthenium reduction was as against the treatment T1 (Glyphosate 71 SG + 2, 4-D ready mixture 3 kg ha -1) followed by T2 (Glyphosate 71 SG @ 3 kg ha -1). The maximum total bacteria (90.40), fungi (90.74) and actinobacteria (68.07) was recorded under T1(Glyphosate+2, 4-D ready mixture 3 kg ha -1) followed by T2 (Glyphosate 71 SG @ 3 kg ha-1). Thus application of these herbicides were safe and may be used to manage this invasive weed plant in non-crop land.
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